We describe herein a Cu(OTf)2 catalyzed oxidative arylation
of a tertiary carbon-containing substrate including aryl malononitriles,
3-aryl benzofuran-2-ones, and 3-aryl oxindoles. In some cases, the
nitrile groups of the aryl malononitriles undergo further reactions
leading to lactones or imines. These reaction conditions are applicable
for a range of arenes, including phenols, anilines, anisoles, and
heteroarenes. Mechanistic studies support the formation of a cationic
intermediate via a two-electron oxidation.
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