Use of complementary and alternative medicine among cancer patients during radiation therapy may affect the degree of radiation toxicity. Further randomized controlled clinical trials are needed to determine the benefits and risks of complementary and alternative medicine use during radiation therapy.

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Aim: In this study, we aimed to evaluate the overall and progression-free survival, the radiotherapy process and the early and late adverse effects in patients who underwent radiotherapy (RT) for primary nervous system lymphoma in our clinic.Method: Between January 2010 and September 2019, 16 patients who received radiotherapy due to primary central nervous system lymphoma in our clinic were examined according to their statistically significant differences in terms of survival and side effects.Results: The median disease-free survival of the patients was 6 months, and the median overall survival was 12.5 months. 18.75% of the patients could not receive chemotherapy but only radiotherapy. Radiotherapy doses were range from 2600 to 5000 cGy. When patients were evaluated in terms of radiotherapy dose, field size and chemotherapy, no statistically significant difference in overall survival was detected. Cognitive disorders were observed as the most common late side effects while the most common acute side effects in patients were headaches.Conclusion: In the treatment of primary central nervous system lymphoma, changes in radiotherapy portals and radiotherapy doses can be predicted in patients who received high-dose methotrexate chemotherapy or not. Furthermore, it has been considered that more comprehensive studies are needed to increase the success of treatment and provide standardization in treatment, especially in patients with elderly and comorbid diseases.

Background: It was aimed to evaluate the differences and relationship between the anthropometric characteristics of the patients who received radiotherapy in our clinic after breast-conserving surgery due to breast cancer. Methods: A total of 40 patients underwent whole breast and lymph node irradiation after breast-conserving surgery were evaluated according to dosimetric parameters and ​anthropometric variables such as weight, mid-sternum thickness, Haller index, central lung distance (CLD) and breast volume.Results: In internal mammary node (IMN) irradiated patients, lung doses (V5, V10, V20, V30, minimum dose (Dmin) and maximum dose (Dmax)) and contralateral breast doses (Dmax and V5) were significantly higher than the patients not received IMN irradiation. Also, breast size shown to be an important factor; when small and large breast sized patients were compared, ipsilateral lung V10, V20, and V30 values and the Dmin of heart were higher in patients with large breast volume. The V5 value and Dmin of the total lung were higher in the group with a CLD value of 3 cm or less. The contralateral breast Dmax and V5 doses were higher in patients with midsternum thickness above 1.7.Conclusions: In the radiotherapy of breast cancer especially for the patients with nodal treatment volumes, differences in treatment designs could be made according to anthropometric variables. In the evaluation of radiotherapy treatment plans individual features like chest wall shape and breast size should be kept in mind.

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