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Sargramostim at both 4 and 6 mg/kg was well tolerated. PK analysis suggested dose proportionality unaffected by CS exposure. Remission and response data are encouraging, but further trials are needed to assess efficacy.

NUTRITION I N SICKLE CELL ANEMIA (HE SS). E l l i o t t 930 Vichinsky, Me1 Heyman, Deborah Hurst, D a n n m Barbara G a f f i e l d , Karen T h o m p s a K l a r a Kleman, Bertram Lubin. C h i l d r e n ' s Hosoital Medical Center o f Northern C a l i f o r n i a. Oakland: O e o a r h e n t o f ~G i a t r i c s. UCSF. To e v a l i a t e the r o l e ' o f n u t r i t i o n i n Hb S S ' W~ performed anthropometric and l a b o r a t o r y measurements on 95 Hb SS p a t i e n t s and determined the e f f e c t s o f c a l o r i c supplementation on these parameters and on c l i n i c a l course. Height and weight were both ERYTHROCYTE CREATINE LEVELS (EC) AN0 THE 933 DIAGNOSIS OF. HEMOLYTIC DISEASE I N NEWBORN INFANTS

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