A biosafety laboratory is a prerequisite for studying emerging infectious diseases. Safe and effective operation in laboratories and the handling of pathogens determine the safety of the personnel, pathogens, and the environment in the laboratory, which are among the key factors for successful experimentation. In this article, we aimed to provide ideas for the emergency management of biosafety laboratories, including a discussion on the urgency of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) related experimental activities, tracking clinical information, taking emergency measures, revision of the risk assessment process, and standardization of personal protective equipment and personnel behavior standards.
The pandemic of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused great pressure and resulted in tragic consequences to the global public health and medical system. A massive Coronavirus Disease 2019 vaccination campaign is underway worldwide. 1 Although pregnant women are prone to a higher risk of COVID-19, clinical trials for the vaccines excluded pregnant and lactating women. Maternal infection may not only lead to premature delivery, abortion, and other adverse pregnancy outcomes but also increase the possibility of infection after childbirth. 2,3 Epidemiological studies have found that prenatal infection is a risk factor for a range of neurological disorders, accompanied by an increased risk of schizophrenia, working memory defects, and executive dysfunction. 4 Maternal infection disrupts the immune balance between the maternal and fetal environments, leading to changes in the immune profile in the developing brain. 5 The infection of pregnant women leads to the increase in cytokines such as interleukin-6, which can pass through the placenta and act on placental cells to stimulate the production of downstream
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