It seems useful to analyze the prognostic significance of LODDS in other samples of HNC.
Background/aim: Acute mesenteric ischemia (AMI), one of the gastrointestinal system complications, which occurs following cardiac surgery, is challenged in the literature with a diminished incidence of AMI by heart surgery without cardiopulmonary bypass (CPB) or with pulsatile CPB. This study aims to compare the incidence and mortality rate of mesenteric ischemia in a series of consecutive patients undergoing coronary artery bypass grafting (CABG) through on-pump and off-pump techniques. Materials and methods: This study included patients who underwent CABG between 1 January 2010 and 31 June 2016. All patients were divided into two groups: Group 1 comprised 6396 CABG patients operated on with the off-pump technique. Group 2 included 1210 patients who received CABG with the on-pump technique. Preoperative data were collected on the studied variables. Postoperative data included the development of intestinal ischemia and in-hospital mortality. Results: Of 7606 consecutive CABG patients, a total of 31 (0.4%) developed intestinal ischemia. The incidence of postoperative mesenteric ischemia was 0.28% in Group 1 and 1.07% in Group 2 (P = 0.000). The survival rates after AMI were 61.1% in Group 1 (offpump) and 7.7% in Group 2 (on-pump) (P = 0.003). Time from the first occurrence of nonspecific GI complaints to laparotomy was similar in the off-pump and on-pump groups and had no effect on mortality. Conclusions: With regard to the incidence of mesenteric ischemia and survival after laparotomy, off-pump CABG patients revealed significant improvement compared with those operated on with the on-pump technique.
© Trakya Üniversitesi T p Fakültesi Dergisi. AVES Yay nc l k taraf ndan bas lm t r. Her hakk sakl d r. © Medical Journal of Trakya Amaç:Helikobakter pilori (H. pilori) gastrik ve duodenal ülser, non-ülser dispepsi, atrofik gastrit, mide kanseri ve MALT lenfomas etiyolojisinde rol oynamaktad r. Çal mam zda Trakya bölgesinde beni n gastroduodenal hastal klarda H. pilori infeksiyonu prevelans arat r lm t r. Gereç ve Yöntemler: Trakya Üniversitesi T p FakültesiEndoskopi Ünitesine ba vuran ve beni n gastroduodenal hastal klar saptanan 4714 hastada retrospektif olarak H. pilori infeksiyonu prevelans ara t r ld .Bulgular: Hastalar n %52.8'inde H. pilori pozitif saptand . H. pilori bulber ülser hastalar nda %65, gastrik ülserli hastalarda %60.2, gastritli hastalarda ise %48.4 oran nda pozitif bulundu (p<0.001). Trakya böl-gesi kökenli hastalar n %52'sinde, Anadoludan göç eden hastalar n %56.3'ünde, Avrupadan göç eden hastalar n %48.7'sinde H. pilori pozitif bulundu (p=0.02). Helikobakter pilori kad nlarda %53.2, erkeklerde %52.2 oran nda pozitifti (p=0.52). Üreaz pozitifli i 30-60 aras ndaki hastalarda 30 ya ndan küçükler ve 60 ya ndan büyüklere göre daha fazlayd . Sonuç:Trakya bölgesinde H. pilori infeksiyonu hem ülkemizin di er bölgeleri ile hemde kom u avrupa ülke-leri ile benzer epidemiyolojik özellikler göstermektedir.
Original Article ÖZET Amaç: Bu çalışma radikal olarak rezeke edilmiş nonmetastatik kolorektal kanserlerde lenf nodu oranın (LNO) prognostik önemini belirlemek için yapılmıştır. Gereç ve Yöntemler:Servisimizde nonmetastatik kolorektal kanser nedeni ile opere edilen 280 hastanın karakteristik ve patolojik özellikleri retrospektif olarak incelenerek kaydedildi. Metastatik lenf nodlarının çıkarılan toplam lenf noduna oranının 1 /12, ¼, ½ ve 1 arasında olmasına göre hastalar 4 gruba ayrıldı. Demografik özelliklerinin dağılımları ve ihtimal tabloları ANOVA ve ki-kare testi ile yapıldı. LNO, N evresi ve TNM evresine göre kümülatif sağkalım oranlarını hesaplamak için Kaplan Meier metodu kullanılırken, gruplar arasında sağkalım farkını hesaplamak için Log rank testi kullanıldı Bulgular: Metastatik lenf nodu sayısı ile LNO arasında istatistiksel olarak anlamlı bir korelasyon oranı mevcuttu (Pearson korelasyon katsayısı (r)=0.674, p<0.001). Hastaların 173 tanesinde (%61.8) 12'den daha az lenf nodu çıkarılmıştı. Değerlendirmede 166 hasta (%59.3) N0, 79 hasta (%28.2) N1 ve 35 hasta (%12.5) N2 olarak tespit edildi. LNO göre oluştu-rulan 4 gruptaki hasta sayıları sırası ile 174 (%62.1), 72 (%25.7), 22 (%7.9) ve 12 (%4.3) idi. LNO1 grubunda 5 yıllık sağkalım oranı %82,8 iken, LNO2 grubunda %69.4, LNO3 grubunda %58.3 ve LNO4 grubunda %50 olarak tespit edildi. Bu gruplar arasındaki fark sağkalım süresi ve oranları açısın-dan istatistiksel olarak anlamlı idi (p=0.001).Sonuç: Doğru evreleme için yetersiz lenf nodu çıkarılmış hastalarda LNO adjuvan tedaviye karar vermede ve prognozu kestirebilmede hekimlere yol gösterecek önemli parametrelerden biri olabilir. ABSTRACT Objective: This study was designed to assess the prognostic value of lymph node ratio (LNR) in patients with nonmetastatic colorectal cancer treated with radical resection. Material and Methods:The characteristic and pathologic parameters of 280 patients operated on for nonmetastatic colorectal cancer at our service were recorded retrospectively. Patients were stratified into 4 groups according to the LNR quartiles of 1 /12, ¼, ½ and 1. Distribution of demographic data and probability tables were made by ANOVA and χ 2 tests. The cumulative survival ratios for LNR, N stage and TNM stage were calculated by the Kaplan Meier method and survival difference between groups were calculated by the log rank test.Results: There was a statistically significant correlation ratio between metastatic lymph node count and LNR. In 173 of all patients (61.8%) fewer than 12 lymph nodes were harvested. One hundred sixtysix (59.3%) patients were evaluated as N0, 79 (28.2%) were N1 and 35 (12.5%) were N2. The number of patients in 4 groups of LNR were 174 (62.1%), 72 (25.7%), 22 (7.9%) and 12 (4.3% ) respectively. Five year survival ratios were 82,8% in LNR1, 69.4% in LNR2, 58.3% in LNR3 and 50% in LNR4. The difference for survival times and ratios between these groups were significantly difference (p=0.001).Conclusion: LNR may help physicians to decide the adequate treatment and estimate th...
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