Objectives
Herbal medicines, as a treatment method, have received a great deal of attention. The effects of two herbal medicines namely Zingiber officinale and Echinacea on alleviation of clinical symptoms and hospitalization rate of suspected COVID-19 outpatients were examined.
Methods
A clinical trial with 100 suspected COVID-19 outpatients as participants was conducted. The participants were allocated randomly to two groups of 50 members. The intervention group received concurrent Zingiber officinale (Tablet Vomigone 500 mg II tds) and Echinacea (Tablet Rucoldup I tds) for seven days in addition to the standard treatment. The control group only received the standard treatment (Hydroxychloroquine). After seven days, alleviation of clinical symptoms and hospitalization rate were examined. In addition, 14 days after treatment, the hospitalization was assessed again by telephone follow up.
Results
The two groups were identical in terms of basic characteristics. Improvement level as to coughing, dyspnea, and muscle pain was higher in the intervention group (p value <0.05). There was no significant difference between the two groups in terms of the other symptoms. In addition, the hospitalization rate in the intervention and control groups were 2 and 6% respectively, which are not significantly different (p value >0.05).
Conclusions
Taking into account the efficiency and trivial side-effects of Zingiber officinale and Echinacea, using them for alleviation and control of the clinical symptoms in COVID-19 outpatients is recommended.
A novel electrochemical sensor based on the reduced graphene oxide-Cu/CuO-Ag nanocomposite modified glassy carbon electrode (rGO/Cu/CuO-Ag/GCE) has been applied for the simultaneous analysis of carbaryl and fenamiphos as two important pesticides. The electrochemical behavior of carbaryl and fenamiphos at rGO/Cu/ CuO-Ag/GCE was studied by cyclic voltammetry and differential pulse voltammetry. The modified electrode exhibited two separated oxidation signals for the simultaneous determination of both carbaryl and fenamiphos with excellent sensitivity. The characteristics of the modified electrode were studied with transmission electron microscopy, X-ray diffraction and Fourier transform-infrared spectroscopy techniques. Under optimized conditions, the rGO/Cu/CuO-Ag/GCE detected carbaryl and fenamiphos with the wide linear ranges of 0.05-20 and 0.01-30 μM, and the detection limits were 0.005 and 0.003 μM, respectively. This developed electrochemical platform applied as a simple and cost-effective sensor for the detection of low levels of carbaryl and fenamiphos in fruit and vegetable samples successfully.
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AimsThere is a rapid increase in the number of people infected with COVID-19 throughout the world. The present study aimed to determine people's knowledge, attitudes, and practices (KAP) regarding COVID-19 in an Iranian sample.Instruments & Methods This was a population-based cross-sectional study conducted on people over 18 years of age in Saveh city, of Iran, in 2020. A multiple-stage sampling method was used. Participants (N=471) completed an anonymous and self-report questionnaire assessing socio-demographic variables and KAP. Data were analyzed using ANOVA and independent t-tests by SPSS 21. The significance level was considered to be ≤0.05. Findings Of participants, 74.5% did not have accurate knowledge of how the coronavirus is spread. In terms of attitudes, more than 63.2% considered COVID-19 to be a dangerous disease. About 59.6% of participants reported regular use of a mask in the past week. As compared to men, women reported attitudes and practices more aligned with recommended safety standards. Higher education level was significantly related to the mean KAP score (p<0.05). Conclusions Although the sample evidenced appropriate attitudes and some safety practices in general, a significant percentage of individuals did not engage in protective behaviors.
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