Sickle cell disease is the commonest single gene disease in Africa. Morbidity and mortality from this disease has remained unacceptably high in Africa whereas there has been a marked reduction in the burden of this disease in the developed countries. This reduction was not achieved through the use of sophisticated care such as bone marrow transplant, but through the adoption of a Comprehensive Health Care Management protocol for sickle cell disease. This protocol of care emphasizes prevention of crises through effective management of the disease. In Africa, where sickle cell disease is prevalent, this strategy of care is yet to be globally adopted. In 2003, this protocol of care was adopted at the University of Benin Teaching Hospital, Nigeria and this has contributed to the improved clinical status of children with sickle cell disease in the hosthe involvement of several professionals such as the genetic counsellor, paediatric haematologist and the social worker among others. This multidisciplinary approach offers a holistic form of care to children with
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