A new series of four transition metal complexes of a Schiff base derived from salicylaldehyde and glycine, viz. [N-salicylidene glycinato diaqua cobalt (II) dimer] (SGCo)2, [N-salicylideneglycinato-di-aqua-nickel(ll)dimer] (SGN)2, [N-salicylideneglycinato-aqua-copper(II)] (SGC) and [N-salicylidene glycinato diaqua zinc(II) dimer] (SGZ)2 have been synthesized and characterized through a rapid, simple, and efficient methodology in excellent yield. These compounds were screened for In Vitro antibacterial activities against six pathogenic bacteria, such as Shigella sonnei, Escherichia coli, Bacilus subtilis, Sarcina lutea, Staphylococcus aureus and Pseudomonas arioginosa. The antibacterial activity was determined by the disc diffusion method using DMSO as solvent. The results indicate that (SGC) compound exhibit a significant antibacterial activity, depending on the bacterial strain and (SGCo)2, (SGN)2 and (SGZ)2 compounds show a moderate sensitivity even with higher doses. All these compounds were found to possess cytotoxic effect.
Bangladesh relies mainly on groundwater for irrigation and drinking purposes. Groundwater, however, continuously polluted, is a major obstacle. Nowadays, Bangladesh is moving towards industrial revolution in a considerable speed. As part of this paper's attempt to analyze the groundwater pollution scenario in Bangladesh, specifically in the past two decades, about 100 articles, conference papers, and reports published in national and international journals and books were reviewed, as well as issues concerning pollution sources, health impact assessment, and future perspectives were discussed. The groundwater is contaminated by different contaminants, such as physico-chemicals, trace metals, and microbes. Human health is at great risk from arsenic (As) contamination; it is one of the biggest threats. The cancer risk and non-cancer risk of ingesting water are increased. On the other hand, a large number of peoples were affected due to waterborne diseases governed by microbial contamination. Geophysical and anthropogenic sources, the depth of wells, and geographical factors may influence groundwater pollution. It is recommended that policy makers should address the issue immediately and precautions should be taken wherever necessary.
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