The frequency of extreme events (e.g., hurricanes, earthquakes, and floods) and man-made attacks (cyber and physical attacks) has increased dramatically in recent years. These events have severely impacted power systems ranging from long outage times to major equipment (e.g., substations, transmission lines, and power plants) destructions. This calls for developing control and operation methods and planning strategies to improve grid resilience against such events. The first step toward this goal is to develop resilience metrics and evaluation methods to compare planning and operation alternatives and to provide techno-economic justifications for resilience enhancement. Although several power system resilience definitions, metrics, and evaluation methods have been proposed in the literature, they have not been universally accepted or standardized. This paper provides a comprehensive and critical review of current practices of power system resilience metrics and evaluation methods and discusses future directions and recommendations to contribute to the development of universally accepted and standardized definitions, metrics, evaluation methods, and enhancement strategies. This paper thoroughly examines the consensus on the power system resilience concept provided by different organizations and scholars and existing and currently practiced resilience enhancement methods. Research gaps, associated challenges, and potential solutions to existing limitations are also provided. INDEX TERMS Critical review, extreme events, power system resilience, resilience definitions, metrics, and enhancement strategies. MOHAMMED BENIDRIS (Member, IEEE) received the B.Sc. and M.Sc. degrees in electrical engineering from the

Byttneria pilosa is locally known as Harijora, and used by the native hill-tract people of Bangladesh for the treatment of rheumatalgia, snake bite, syphilis, fractured bones, elephantiasis and an antidote for poisoning. The present study was carried out to determine the possible anti-inflammatory, analgesic, neuropharmacological and anti-diarrhoeal activity of the methanol extract of B. pilosa leaves (MEBPL) through in vitro, in vivo and in silico approaches. In the anti-inflammatory study, evaluated by membrane stabilizing and protein denaturation methods, MEBPL showed a significant and dose dependent inhibition. The analgesic effect of MEBPL tested by inducing acetic acid and formalin revealed significant inhibition of pain in both tests. During the anxiolytic evaluation, the extract exhibited a significant and dose-dependent reduction of anxiety-like behaviour in mice. Similarly, mice treated with MEBPL demonstrated dose-dependent reduction in locomotion effect in the open field test and increased sedative effect in the thiopental sodium induced sleeping test. MEBPL also showed good anti-diarrheal activity in both castor oil induced diarrheal and intestinal motility tests. Besides, a previously isolated compound (beta-sitosterol) exhibited good binding affinity in docking and drug-likeliness properties in ADME/T studies. Overall, B. pilosa is a biologically active plant and could be a potential source of drug leads, which warrants further advanced study.

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