Background and aims: neonatal mortality in pregnant women with pre-eclampsia remains a concern in our environment and several factors, including those related to complications of pre-eclampsia, contribute to it in our settings where the care is inadequate. The aims of our study is to determine the frequency of transfer to describe the survival of babies born to preeclampsia mothers admitted to the Pediatric Neonatology Department of University Clinics of Kinshasa over a consecutive period of approximately 30 days. Methods: This is a prospective cohort study carried out over a period from January 1, 2006 to December 31, 2015 targeting all babies born to preeclampsia mothers followed in the neonatal service of the University Clinics of Kinshasa. Maternal, perpartal, neonatal and evolutionary characteristics (cure or death) were studied. Survival was described by the Kaplan Meier method at the 5% significance level. Results: the recorded death rate was 26.5%. Gestational age between 28-36 weeks of amenorrhea conferred a risk of death in children 3 times, compared with APGAR <7 at the 1st, 5th and 10th which conferred a risk of 2, 3 and 3 times respectively. The overweight-obese mothers had a risk doubled of causing the death of newborns. Conclusion: The toll of neonatal mortality during preeclampsia is heavy in developing countries where newborns continue to die from often preventable causes. The reduction in neonatal morbidity and mortality requires an improvement in the system of care for newborns in our environment.
Background and aims: the progression of preeclampsia continues to increase in sub-Saharan Africa where care is inadequate. The objective of this study is to identify factors associated with the progression of preeclampsia at University Clinics of Kinshasa. Methods: This is a prospective and analytical study of 265 patients hospitalized at the Gynecology Service of the University Clinics of Kinshasa between January 1, 2006 and December 31, 2015. The clinical, biological, therapeutic and evolutionary characteristics were the parameters of 'interest. Cox regression in multivariate analyzes was generated to identify risk factors for progression to the p <0.05 threshold. Results: The cumulative frequency of preeclapse decreased from 6.0% in the first year to 64.2% at the end of the study with periods of stagnation in the rate. Predictors of the progression of preeclampsia in the study population for F values equal to 2.86, 2.10, 3.57, 3.23, 2.81 and 0.005 and an α risk equal at 0.009; 0.014; 0.006; 0.007; 0.005 and 0.006 0.0005, respectively, for age, level of education, occupation, SAP, DBP and figure 3, led us to reject the null hypothesis of equality of means between progression and the lack of progression. In multiple cox regression, the risk of progression of preeclampsia was 3 times respectively in parturients aged > 35 years (aRR: 2.57 95% CI: 1.89-4.75), in female employees (aRR: 2.83 95% CI: 1.97-4.46); this risk was 2 times respectively among academics, PAS and PAD elevated. Treatment under scheme 3, on the other hand, reduced the risk of progression 2 (aRR: 0.43 95% CI: 0.28-0.63). Conclusion: the progression of pre-eclampsia could be linked to certain socio-demographic and clinical factors. The role played by the treatment regimen of αmethyl Dopa + Nifedipine + Diazepam remains to be defined in this subgroup.
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