The inclusion mode of 8-anilino-1-naphthalenesulfonate (ANS) in the ANS-β-cyclodextrin complex with a molar ratio of 1 : 1 in deuterium oxide was investigated by measurements of the proton nuclear magnetic resonance spectra and studies with Corey Pauling Koltun models. It was found that in the preferential inclusion mode of ANS, the whole benzene ring of ANS is enclosed at a considerable depth in the cavity of β-cyclodextrin from the side of the secondary hydroxyl group, and a great portion of the naphthalene ring is outside the cavity.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.