In this work different heterocyclic compounds derivatives were synthesized using ortho-Carboxybenzaldehyde as a starting material which reacted with different aromatic amines to produce Schiff bases. These Schiff bases introduced in three types of reactions using different reagents (Chloroacetylchloride, Thio acetic acid, Malic anhydride and Phthalic anhydride) to give the target heterocyclic compounds four, five and seven heterocyclic compounds derivatives. The structure of these compounds identified by FT-IR and some of them by 1 H-NMR spectra