Objective: To evaluate the prevalence of and factors associated with SARS-CoV-2 infection in general practitioners and nurses from primary care centers and nursing homes in the Healthcare Area of León (Spain). Materials and methods: Cross-sectional study in a convenience sample of professionals from 30 health centers and 30 nursing homes from the primary care management division of the Healthcare Area of Leon. The work center, type of profession, COVID-19 infection, level of exposure, compliance with preventive measures, isolation (if required) and diagnostic tests carried out were collected. The determination of infection was made by differentiated rapid diagnostic test (dRDT), using a finger-stick whole-blood sample. The association of variables with infection was assessed by multivariable non-conditional logistic regression. The true prevalence of SARS-CoV-2 infection was calculated according to two scenarios for RDT (Sensitivity = 0.6 and Specificity = 0.985; Sensitivity = 0.8 and Specificity = 1).

The county-wide lockdowns that were implemented due to the COVID-19 pandemic resulted in some in-person qualitative research studies needing to be transitioned online using a video conferencing platform. However, evaluating the feasibility of transitioning an ongoing qualitative research study focused on low-income, racial/ethnic minorities had not been performed. Orsmond and Cohn’s feasibility framework was used to evaluate this study in three primary areas: recruitment capability, data collection procedures, and evaluation of relevant resources. Recruitment efforts for the in-person focus groups (January–March 2020) and online focus groups (March–April 2020), along with data collection procedures, were measured through various counts. To gauge the resources needed to transition a study from in-person to online, the administrative capacity, the space, technology, and funds necessary to support the research study were recorded. Sample characteristics were extracted from administrative and survey data. To estimate the differences in the sample characteristics, recruitment efforts and the length of the focus groups before and during the lockdown, independent sample t-tests, or proportion tests were conducted. The sociodemographic characteristics of participants pre-lockdown and during the lockdown were similar between the two groups with most participants identifying as female, Black, single, unemployed. The average number of participants recruited, confirmed, and attended per focus group, along with the total number of contact attempts remained similar before and during the lockdown. The length of the focus groups before and during the lockdown also remained similar. The in-person focus groups did require more financial resources for their successful execution than the online focus groups. It is feasible to sustain a research study focused on low-income, racial/ethnic minorities by transitioning the study from in-person to online using a video conferencing platform. This approach should be considered from the onset of qualitative research studies to increase reach to low-income, racial/ethnic minorities.