The measurement of blood pressure in the premature neonate presents many difficulties. A new device has been developed which allows the noninvasive determination of mean arterial pressure (MAP). The device uses an occluding cuff which may be placed on any of the extremities and chooses as MAP the lowest cuff pressure at which the oscillations in cuff pressure are maximum.The device was tested in a series of 36 studies involving eleven infants whose weights ranged from 3.3 Kg to 800 h. The studies were conducted by comparing the pressure measured using the indirect device, with that pressure measured from an umbilical artery catheter. Where possible, determinations were made on the forearm, bicep, calf, and thigh. Where this was not possible, only the thigh or the bicep was used. The mean error between the two methods was .86 mmHg and the average standard deviation was 2.9 mmHg.Although the measurement of blood pressure in m a l l infants remains more difficult than similar measurements in adults, it was found that with appropriate precautions, accurate results could be achieved over a wide rsnge.of pressures and physiological states. Increased survival of high-risk infants (HRI) born in tertiary care centers has led to the concept that in utero transportation of the HRI is superior to postpartum infant transportation. We evaluated this concept by comparison of 40 infants transported in utero (IUT) with 40 infants transported in the first postpartum day (PPT). Infants were selected by comparing all IUT with the next consecutive admission transported from the same town or an equal distance (+Somi). Infants were then matched for gestational age (+2wk), birth weight (+100gm), and primary neonatal disease. Transport mortalities and other features of the two groups were then carefully analyzed for significance.
THE VALUE OF CONTINUOUS POSITIVE AIRWAY PRESSURE IN
1016The IUT were no different from the PPT in number of mothers with >1 risk factor, toxemia, diabetes, or multiple births. More of the PPT were preterm (p<.05) and more IUT suffered premature rupture of membranes (p<.005). No differences were found in Apgars pH, TSP, serum glucose, or primary neonatal disease. Neither group suffered significant hypothermia. 37 infants required ventilation but no differences existed in peak ambient oxygen or end expiratory pressure requirements. Mean age of PPT at admission was 7.7 hours, and mean transport distance was 100 mi. Transport mortality was 12%, 10%. for IUT, PPT, respectively. Survival time for infants expiring in the first month and hospitalization time for neonatal survivors were similar. This study suggests that early PPT may be as valuable as IUT for the high-risk newborn. ACUTE SUDDEN HYPERTENSION IN THE NEWBORN PERIOD. 101s Ekkehard W. Reimold. Univ. of Texas, Southwestern Med. School, Dept. of Pediat., Dallas, Texas. After an initial normotensive period the blood pressure rose in 3 infants at the age of 6 days, 8 days and 4 weeks to 180-230 mmHg. In each case an umbilical artery catheter had been inserted be...