Gluconacetobacter liquefaciens is a Gram-negative bacterium that has previously been described as a plant pathogen. To the best of our knowledge, only one previous case of human infection with Gluconacetobacter species has been described and was associated with severe immunodeficiency. We describe a case of recurrent Gluconacetobacter liquefaciens bacteremia in a patient with advanced liver cirrhosis and propose that gut translocation in the setting of portal hypertension and frequent sugarcane juice ingestion may have been the etiology. This case expands on our knowledge of Gluconacetobacter liquefaciens as a potential emerging human pathogen in certain situations and describes the difficulty encountered in antimicrobial testing and management.
Pregnant women are significantly more likely to have an asymptomatic acute infection with C. burnetii which, untreated, has been associated with poor obstetric outcomes including miscarriage, stillbirth, intrauterine growth restriction, and premature delivery. As such, Q fever is a potentially under-recognised and treatable cause of adverse pregnancy outcomes in rural Northern New South Wales, with testing of Q fever polymerase chain reaction (PCR)—whether on maternal sera or placental tissue—not currently recommended by the Perinatal Society of Australia and New Zealand for Stillbirth.
Mycetoma is a chronic, granulomatous, subcutaneous infection caused by several species of fungi and soil-inhabiting bacteria, and is divided into eumycetoma and actinomycetoma, respectively. Endemicity is described with worldwide distribution within the “mycetoma belt”; however, the global burden is ill-defined. Mycetoma is rare in Australia, with only a few published case reports. Over time, the breadth of eumycetoma pathogens has expanded with local epidemiology accounting for variations in regional prevalence. Direct inoculation of pathogens typically heralds the triad of subcutaneous mass, sinus formation and discharging grains. We describe a case of eumycetoma in a 48-year-old male Filipino renal transplant recipient who presented with a painless slow-growing elbow lesion. Ultrasonography revealed two ovoid masses and surgical excision ensued. Histopathology revealed necrotising granulomata with numerous chestnut-brown thick-walled cells, septate hyphae, and occasional grains. On suspicion of localised chromoblastomycosis, the isolate was sent to a reference laboratory which identified the fungus as Falciformispora lignatilis, an organism not hitherto associated with human infection. Amongst the solid organ transplant cohort, similar atypical presentations have been described. Clinicians need to consider eumycetoma where an epidemiological link with the tropics exists, especially in atypical presentations in transplant recipients, including absent preceding trauma.
Please cite this article as: Olenski M et al., Mecillinam susceptibility in Victorian third generation cephalosporin-nonsusceptible Escherichia coli urinary isolates, Pathology,
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.