The reactions of anhydrous metal chlorides MCl 2 [M = Co(II), Zn(II), Pd(II)] with aziridines (az) in CH 2 Cl 2 at r. t. in a 1 : 5 molar ratio afforded the bis(aziridine)dichloro complexes M(az) 2 Cl 2 . After purification, all complexes were fully characterized. The solid state structures were determined using single crystal X-ray diffraction, and showed tetrahedral coordination geometries for the Co(II) and Zn(II) centers and trans-configurated square planar geometries for Pd(II).
Two isomers of the [Co(tren)(D-Glc1A1,2H −2 -κ 2 O 1,2 )] + (1) chelate are formed in equal parts in the reaction of [Co(tren)Cl 2 ]Cl and sodium gluconate. In contrast, the gluconate's 2-amino-2-deoxy derivative glucosaminate formed a single isomer of [Co(tren)(2). Crystals of the OC-6-34 isomer of 1, [1a]PF 6 ·H 2 O, showed the support of the metal-binding site by intramolecular hydrogen bonds. Due to the inertness of the cobalt(III) chelates, spectroscopy on redissolved crystals of [1a]PF 6 ·H 2 O allowed the separation of the two 13 C NMR signal sets of the isomeric mixture. In a DFT approach, a small energy difference explained the formation of two isomers in the case of the gluconate. A larger difference was obtained for the glucosaminate, in line with the known rules for the stereospecific amino acid-Co(tren) chelation.
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