Plasmonic nanostar-dimers, decoupled from the substrate, have been fabricated by combining electron-beam lithography and reactive-ion etching techniques. The 3D architecture, the sharp tips of the nanostars and the sub-10 nm gap size promote the formation of giant electric-field in highly localized hot-spots. The single/few molecule detection capability of the 3D nanostar-dimers has been demonstrated by Surface-Enhanced Raman Scattering.

Topology control, wherein nodes adjust their transmission ranges to conserve energy and reduce interference, is an important feature in wireless ad hoc networks.Contrary to most of the literature on topology control which focuses on reducing energy consumption, in this paper we tackle the topology control problem with the goal of limiting interference as much as possible, while keeping the communication graph connected with high probability. Our approach is based on the principle of maintaining the number of physical neighbors of every node equal to or slightly below a specific value k. As we will discuss in this paper, having a non-trivially bounded physical node degree allows a network topology with bounded interference to be generated. The proposed approach enforces symmetry on the resulting communication graph, thereby easing the operation of higher layer protocols. To evaluate the performance of our approach, we estimate the value of k that guarantees connectivity of the communication graph with high probability both theoretically and through simulation. We then define k-Neigh, a fully distributed, asynchronous, and localized protocol that uses distance estimation. k-Neigh guarantees logarithmically bounded physical degree at every node, is the most efficient known protocol (requiring 2n messages in total, where * Parts of this paper appeared in Proc. ACM MobiHoc 03 [5]. † Georgia Inst. of Technology, Atlanta GA -USA. e-mail: doug.blough@ece.gatech.edu ‡ Università di Modena e Reggio Emilia and IIT-CNR -ITALY. e-mail: leoncini@unimore.it § IIT -CNR, Pisa -ITALY. e-mail: {giovanni.resta, paolo.santi}@iit.cnr.it 1 n is the number of nodes in the network), and relies on simpler assumptions than existing protocols. Furthermore, we verify through simulation that the network topologies produced by k-Neigh show good performance in terms of node energy consumption and expected interference.

We propose an approach to topology control based on the principle of maintaining the number of neighbors of every node equal to or slightly below a specific value k. The approach enforces symmetry on the resulting communication graph, thereby easing the operation of higher layer protocols. To evaluate the performance of our approach, we estimate the value of k that guarantees connectivity of the communication graph with high probability. We then define k-Neigh, a fully distributed, asynchronous, and localized protocol that follows the above approach and uses distance estimation. We prove that k-Neigh terminates at every node after a total of 2n messages have been exchanged (with n nodes in the network) and within strictly bounded time. Finally, we present simulations results which show that our approach is about 20% more energy-efficient than a widelystudied existing protocol.

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The aim of this paper is to expound on the rational design, fabrication and development of superhydrophobic surfaces (SHSs) for the manipulation and analysis of diluted biological solutions. SHSs typically feature a periodic array or pattern of micropillars; here, those pillars were modified to incorporate on the head, at the smallest scales, silver nanoparticles aggregates. These metal nanoclusters guarantee superior optical properties and especially SERS (surface enhanced Raman scattering) effects, whereby a molecule, adsorbed on the surface, would reveal an increased spectroscopy signal. On account of their two scale-hybrid nature, these systems are capable of multiple functions which are (i) to concentrate a solution, (ii) to vehicle the analytes of interest to the active areas of the substrate and, therefore, (iii) to measure the analytes with exceptional sensitivity and very low detection limits. Forasmuch, combining different technologies, these devices would augment the performance of conventional SERS substrates and would offer the possibility of revealing a single molecule. In this work, similar SHSs were used to detect Rhodamine molecules in the fairly low atto molar range. The major application of this novel family of devices would be the early detection of tumors or other important pathologies, with incredible advances in medicine.

In this paper we consider a constrained version of the range assignment problem for wireless ad hoc networks, where the value the node transmitting ranges must be assigned in such a way that the resulting communication graph is strongly connected and the energy cost is minimum. We impose the further requirement of symmetry on the resulting communication graph. We also consider a weaker notion of symmetry, in which only the existence of a set of symmetric edges that renders the communication graph connected is required. Our interest in these problems is motivated by the fact that a (weakly) symmetric range assignment can be more easily integrated with existing higher and lower-level protocols for ad hoc networks, which assume that all the nodes have the same transmitting range. We show that imposing symmetry does not change the complexity of the problem, which remains NP-hard in two and three-dimensional networks. We also show that a weakly symmetric range assignment can reduce the energy cost considerably with respect to the homogeneous case, in which all the nodes have the same transmitting range, and that no further (asymptotic) benefit is expected from the asymmetric range assignment. Hence, the results presented in this paper indicate that weak symmetry is a desirable property of the range assignment. R. Baeza-Yates et al. (eds.

A novel electrowetting-on-dielectrics (EWOD) device in open planar geometry allows probing of droplet mixing on a superhydrophobic substrate under quasi contact-free conditions. We demonstrate a droplet-based microreactor with integrated convective-flow mixing for the reactive-mixing of CaCl(2)/Na(2)CO(3) solutions. The device provides unique conditions for scattering, spectroscopy and imaging probes requiring an unobstructed droplet-access.

Periodic and reproducible gold nanocuboids with various matrix dimensions and with different inter-particle gaps were fabricated by means of top-down technique. Rhodamine 6G was used as a probe molecule to optimize the design and the fabrication of the cuboid nanostructures. The electric field distribution for the nanocuboids with varying matrix dimensions/inter-particle gap was also investigated. These SERS devices were employed as biosensors through the investigation of both myoglobin and wild/mutated peptides. The results demonstrate the probing and the screening of wild/mutated BRCA1 peptides, thus opening a path for the fabrication of simple and cheap SERS device capable of early detection of several diseases.