Zika virus (ZIKV) is an RNA flavivirus (Flaviviridae family) endemic in tropical and subtropical regions that is transmitted to humans by Aedes (Stegomyia) species mosquitoes. The two main urban vectors of ZIKV are Aedes aegypti and Aedes albopictus, which can be found throughout Brazil. This study investigated ZIKV infection in mosquito species sampled from urban forest fragments in Manaus (Brazilian Amazon). A total of 905 non-engorged female Ae. aegypti (22 specimens) and Ae. albopictus (883 specimens) were collected using BG-Sentinel traps, entomological hand nets, and Prokopack aspirators during the rainy and dry seasons between 2018 and 2021. All pools were macerated and used to inoculate C6/36 culture cells. Overall, 3/20 (15%) Ae. aegypti and 5/241 (2%) Ae. albopictus pools screened using RT-qPCR were positive for ZIKV. No supernatants from Ae. aegypti were positive for ZIKV (0%), and 15 out of 241 (6.2%) Ae. albopictus pools were positive. In this study, we provide the first-ever evidence of Ae. albopictus naturally infected with ZIKV in the Amazon region.
O Antígeno Prostático Especifico (PSA) é considerado o mais importante marcador para detectar, estagiar e monitorizar o câncer de próstata. Realizou-se estudo com objetivo de caracterizar os homens que realizaram o exame de dosagem do PSA no ano de 2009 em uma unidade básica de saúde do município de Maringá-PR. Foram coletados informações referentes à idade, raça, resultado do exame de PSA e local de moradia. A variável independente foi os valores do PSA (normal ou alterado). Utilizou-se a estatística descritiva das variáveis através das freqüências e da análise bivariada pelo Teste Exato de Fisher. Constatou-se que 53,5% dos homens que buscaram realizar o exame de PSA eram menores de 60 anos, onde desses, 1,2% tiveram seu nível de PSA alterado ou acima de 4,01Ng-mL. Ser maior de 70 anos foi estatisticamente significativo para PSA alterado. Concluiu-se que a idade é um fator desencadeante para as anomalias prostáticas benignas e malignas.
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