Zika virus is an emerging arbovirus, which is expanding in epidemic proportions through tropical and subtropical areas of the world. Although Zika is linked to a number of congenital and neurological complications, there is scarce knowledge on the impact of ZIKV infection in human skin. We report the case of a 68-year old woman who presented with generalized pustular psoriasis after a preceding and otherwise uneventful episode of ZIKV infection. Based on recent experimental data on the biology of ZIKV infection in the cutaneous environment, we speculate that ZIKV may have directly triggered the development of generalized pustular psoriasis by stimulation of keratinocyte-derived mediators of inflammation and a polyfunctional T-cell driven immune reaction in the cutaneous milieu.
El texto que se reseña a continuación adquiere una particular vigencia toda vez que, y para el “calor” del momento, se constituyó como uno de los escritos que procuró respuestas y reflexiones “en frío”, ya no desde la perspectiva de la pirotecnia mediática o de lo que columnistas de opinión presentaron de manera casi que inmediata aunque sí tomando como referente lo que, en su momento, desde los medios se canalizó hacia la opinión pública.
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