This study reports that there are schizophrenics who do relatively well long
term without the routine or continuous use of antipsychotic medication. Specially selected
young males undergoing an acute schizophrenic episode were followed, after hospitalization,
for up to three years. While hospitalized they were assigned randomly to either placebo or
chlorpromazine treatment. Many unmedicated-while-in-hospital patients showed greater
long-term improvement, less pathology at follow-up, fewer rehospitalizations and better
overall function in the community than patients who were given chlorpromazine while in
the hospital. Factors related to post-hospital outcome were good premorbid history and
short-lived paranoid characteristics. Considerations which may have an effect on the successful
management of acute schizophrenic patients not on medication are mentioned. The
findings underline the need for further study of how to utilize antipsychotic medication
more selectively in the treatment of schizophrenia.
The committee's first report, published in Circulation for June 1953, recommended a terminology and certain conventions for recording ballistocardiograms of the type then in use. However, it soon became apparent that the committee's work was far from complete.Increasing knowledge of ballistic theory soon began to throw light on the relations of records secured by various instruments to one another, and a rapid advance in instrumentation began to provide records related to, but often not identical with, those which had been provided with a standard terminology by the committee in its first report. Accordingly, the committee has continued its labors to provide the rapidly advancing field with a uniform terminology.While they were thus engaged, attention was called to the fact that the designation of spatial axes previously recommended for vector ballistocardiograms differed from that which had been recommended for electrocardiograms by another committee of the American Heart Association. The advantages of a common system for designating spatial axes were obvious to all. Accordingly, as the electrocardiographic usage had priority and as little had been published in the field of ballistocardiographic vectors the committee voted to withdraw their original recommendation and substitute one conforming to that in use by electrocardiographers. In the present communication this new convention is also set forth.All members of the committee have shared in the deliberations and taken part in the decisions which form the basis of this report; but so much of the larger proportion of the actual work fell on Dr. Scarborough and Dr. Talbot that it was agreed without dissenting vote that only their names should appear as authors. This report has the endorsement of the committee as a whole, and the terminology it suggests is recommended as the official terminology of the American Heart Association.
The authors are listed serially in the order of their original association with the project. Dr. Oscar S. Adams also contributed to the early formulation of the concepts and methods underlying this research.
The Disability Rating (DR) and Coma/Near-Coma (C/NC) scales for evaluating severe head injury are described. Scales are related to patient status, course and outcome and also underlying electroneurophysiological dysfunction. They lend themselves to high inter-rater reliability with brief training and can be completed in minutes, conserving staff time and energy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.