103Pd and 125I brachytherapy sources are being used for interstitial implants in tumor sites such as the prostate. Recently, a double-wall 103Pd source has been introduced, which has a design different from that of sources presently on the market. Dosimetric characteristics (dose rate constant, radial dose function, and anisotropy function) of this source were experimentally and theoretically determined following the AAPM Task Group 43 recommendations and were related to the October 10, 2000 revision of the NIST 1999 SK Standard for 103Pd. Measurements were performed in a Solid Water phantom using LiF thermoluminescent dosimeters. For these measurements, slabs of Solid Water phantom material were machined to accommodate the source and LiF TLD chips of dimensions (3.1 x 3.1 x 0.8 mm3) and (1.0 x 1.0 x 1.0 mm3). The TLD chips were surrounded by at least 10 cm of Solid Water phantom material to provide full scattering conditions. The Monte Carlo simulations were performed in Solid Water and liquid water using the PTRAN code. The results of this investigation show an excellent agreement (within 5%) between the measured (0.67+/-8% cGy h(-1) U(-1)) and calculated (to be 0.65+/-3% cGy h(-1) U(-1)) dose rate constant in Solid Water. The Monte Carlo calculated dose rate constant of the Best 103Pd in water was found to be 0.67+/-0.02 cGy h(-1) U(-1). The radial dose function, g(r), of the new 103Pd source was measured at distances ranging from 0.5 and 7 cm using LiF TLD in Solid Water phantom material. Moreover, the radial dose function of the new source was calculated in liquid water and Solid Water at distances ranging from 0.1 to 7 cm using the PTRAN Monte Carlo Code. The anisotropy function, F(r, theta), of the new 103Pd source was also measured in Solid Water and calculated in both Solid Water and water phantom material. From the anisotropy functions, the anisotropy factors, and anisotropy constant were calculated for each medium. The results indicated that the measured anisotropy constant of the Best 103Pd source in Solid Water was 0.89+/-5%. Complete dosimetric data are described in this manuscript.
The TG-43 recommended dosimetric characteristics of a new 125 I brachytherapy source have been experimentally and theoretically determined. The measurements were performed in Solid Watert using LiF TLDs. The calculations were performed using Monte Carlo simulations in Solid Watert and water. The measured data were compared with calculated values as well as the reported data in literature for other source designs. The dose rate constant this source in water was 1.0173% cGy h À1 U À1 and the anisotropy constant was 0.956. r
The dose linearity and uniformity of a linear accelerator designed for multileaf collimation system-(MLC) based IMRT was studied as a part of commissioning and also in response to recently published data. The linear accelerator is equipped with a PRIMEVIEW, a graphical interface and a SIMTEC IM-MAXX, which is an enhanced autofield sequencer. The SIMTEC IM-MAXX sequencer permits the radiation beam to be " ON" continuously while delivering intensity modulated radiation therapy subfields at a defined gantry angle. The dose delivery is inhibited when the electron beam in the linear accelerator is forced out of phase with the microwave power while the MLC configures the field shape of a subfield. This beam switching mechanism reduces the overhead time and hence shortens the patient treatment time. The dose linearity, reproducibility, and uniformity were assessed for this type of dose delivery mechanism. The subfields with monitor units ranged from 1 MU to 100 MU were delivered using 6 MV and 23 MV photon beams. The doses were computed and converted to dose per monitor unit. The dose linearity was found to vary within 2% for both 6 MV and 23 MV photon beam using high dose rate setting (300 MU/min) except below 2 MU. The dose uniformity was assessed by delivering 4 subfields to a Kodak X-OMAT TL film using identical low monitor units. The optical density was converted to dose and found to show small variation within 3%. Our results indicate that this linear accelerator with SIMTEC IM-MAXX sequencer has better dose linearity, reproducibility, and uniformity than had been reported.
This paper compares dose volume histograms (DVHs) generated by the ADAC Pinnacle and the Nomos Corvus planning systems. Seven prostate cases and seven head and neck cases were selected for review. Plans computed on both systems possessed exactly the same anatomical contours and IMRT segments. The Pinnacle system used the collapsed cone convolution superposition, while Corvus employed a finite size pencil beam (FSPB) convolution. Prostate DVH results demonstrated similar DVH curves from both systems. For each structure, the ratio of Pinnacle dose value divided by Corvus value was calculated. The high dose structures (which might contain tumour) had ratios close to unity, while the low dose structures (the critical organs) had ratios farther away from unity. Almost all ratios were less than unity, indicating a systematic difference that Pinnacle calculated doses were lower than Corvus ones. Head and neck data provided similar findings. A possible cause for this discrepancy could be the beam modelling. The difference in DVH parameters that we discovered between the two systems was about the same order of magnitude as the measurement-computation difference. When low dose is critical, such difference may affect the clinical planning decision.
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