A polymersome‐stabilized Pickering emulsion was prepared and applied in a biphasic enzymatic reaction. This type of Pickering emulsion was stabilized by fully packed crosslinked polymersomes at the water/oil interface. CalB, as a model enzyme (red ribbon structure), was loaded either in the water phase or in the lumen of the polymersomes of the Pickering emulsion (see picture), which highly enhanced its catalytic performance and recyclability.

Polymersomes, polymeric vesicles constructed of block copolymers, can undergo a sphere-to-tubule transition under the influence of a chemical modification of the polymeric bilayer. A strain-promoted alkyne-azide cycloaddition (SPAAC) reaction between azide handles inside the hydrophobic domain of the membrane and an excess of a bicyclo[6.1.0]nonyne (BCN)-cross-linker causes the vesicle to stretch in one dimension. Tubular polymersomes up to 2 μm in length can be obtained with this shape transformation. The introduction of a cleavable cross-linker makes this process reversible and opens the way for future drug delivery applications.

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Copper-bis(oxazoline) complexes have been immobilised in the hydrophobic domain of a polymersome membrane to perform asymmetric cyclopropanation reactions in aqueous media with enhanced conversions and enantioselectivities.