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This limited series demonstrates excellent graft patency with a low persistent infection rate. Thus, in patients with localized graft infection, partial excision with preservation of the proximal synthetic graft is an acceptable alternative when patient factors preclude complete graft excision.

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Objectives: Percutaneous mechanical thrombectomy (PMT) is a popular and useful tool for thrombus removal in acute thrombotic syndromes. The AngioJet uses high-pressure spray to break up and aspirate thrombus in addition to delivering plasminogen activators. This is known to cause hemolysis, and all practitioners have noted periprocedural hematuria. Despite this, to our knowledge, there is no study evaluating the consequences to renal function after using this device. We sought to determine the incidence of acute kidney injury, and associated risk factors after using the AngioJet for thrombolysis.Methods: With Investigational Review Board approval, we retrospectively reviewed a prospectively maintained database of all patients managed by the vascular surgery service from 2009-2012 with procedural codes describing thrombolysis (Current Procedural Terminology [CPT] codes 37201, 37187, 37209, and 75898), and/or PMT (CPT 37187). We identified those treated with the AngioJet and reviewed demographics, indications, laboratory values before and after the procedure (up to 3 days), and determined the incidence of acute kidney injury (AKI). AKI was defined as an increase in creatinine (Cr) >25% of baseline within 24 to 72 hours. Patients on dialysis before AngioJet or without laboratory values before and 24 to 72 hours after treatment were excluded.Results: We identified 144 lysis procedures, and 53 were treated with the AngioJet. Average age was 50 (range, 87-20; median, 49). Arterial thrombus was the indication in 68%; venous in the rest. AKI occurred in 15 of 53 (28%). Baseline Cr in AKI and non-AKI patients was similar, whereas Cr after AngioJet was not (P ¼ .01). Only four patients had a baseline Cr >1.4 (two in each group). Average age of the AKI group was 54 (range 36-74, medium 49), 47% were male, and only one had a baseline Cr >1.4 mg/ dL (not significant for all). Average creatinine increase from baseline in AKI group was 0.5 mg/dL (167% rise; P ¼ .003) compared with e0.07mg/dL (NS) in non-AKI patients. When compared with 53 lysis cases that did not use AngioJet, the Cr change in the AngioJet group was higher (P ¼ .03).Conclusions: This preliminary study suggests that AKI may occur in more than one-quarter of patients treated with the AngioJet, independently of traditional risk factors for AKI (diabetes, baseline Cr, and age). This risk may be due to hemolysis and is under-reported in the literature. Prospective studies and long-term consequences should be undertaken to better define this risk.