At the beginning of his youthful sixth decade, this work is dedicated to Prof. Dr. Fabio Doctorovich. He is distinctive in organometallic chemistry. During his successful career, he has been studying the reactivity and application of metalloporphyrins. Metalloporphyrins are organometallic complexes that exhibit, through synthetic modifications, the ability to tune their optical and electrochemical properties and their selectivity towards a particular molecule or ion. For this reason, they are systems extremely useful as electrochemical sensors to detect and quantify a wide variety of analytes with high selectivity, even in real samples such as food, water, biological fluids, or pharmaceutical compounds. This review presents an up-to-date list of reports in which metalloporphyrins are used as electrochemical sensors. In addition to compiling a comprehensive and up-to-date list of reported sensors that utilize metalloporphyrins, this work aims to provide an overview of currently available tools and techniques for the detection of various chemical species through similar approaches, which are constantly being developed.

The Front Cover shows an engaging platform for electrochemical sensor development: Metalloporphyrins. Although the last years have been times of numerous technological transitions, porphyrins have been and currently are critical building blocks in the development of micro‐/nanosensors. In recent years, not only have small molecules been detected and quantified, but it is now also possible to measure relevant macromolecules with high precision in intricate samples. This work presents an up‐to‐date list of reports in which metalloporphyrins are used as electrochemical sensors. Most of them are developed with a blend of porphyrin rings and metals of the first transition series. Renewed efforts in the synthesis, improved electronics, and data analysis will lead to better performance and new applications of metalloporphyrin‐based electrochemical sensors in the coming years. More information can be found in the Review by S. A. Suarez and co‐workers.