Copper(II) triflate catalyzes the ring-opening of aryl-and vinyl-substituted epoxides with various carbonyl compounds to furnish 1,3-dioxolanes under mild conditions. Alkyl-and alkoxycarbonyl-substituted epoxides remain unchanged under reaction conditions. This allows selective opening of aryl-substituted epoxides in the presence of alkyl-substituted ones.
Give 1,3-Dioxolanes. -Epoxides are easily converted into the corresponding 1,3-dioxolanes by a selective and mild ring-opening reaction. -(KRASIK*, P.; BOHEMIER-BERNARD, M.; YU, Q.; Synlett 2005, 5, 854-856; Shire BioChem Inc., Laval, Que. H7V 4A7, Can.; Eng.) -C. Oppel 31-130
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.