A AIDS (síndrome da imunodeficiência adquirida) vem causando calamidades desde sua descoberta, nos anos 80 e infectando cada vez mais as pessoas, e baseando nisso há uma intensa discussão sobre como surgiu essa patologia, suas formas de transmissão, suas causas e consequências no organismo humano e o que fazer para se prevenir da infecção. Foi realizada uma revisão bibliográfica visando sobre no que o exercício físico em si pode contribuir para a manutenção da saúde e tratamento da patologia das pessoas que estão infectadas com o vírus causador da doença. O trabalho foi realizado a partir de uma revisão de literatura, sendo pesquisados artigos científicos publicados entre as últimas três décadas, utilizando os seguintes tópicos isolados ou em combinação: HIV e AIDS, exercícios físicos, benefícios, exercícios de resistência, exercícios de força, exercícios aeróbicos Os resultados demonstraram que o exercício físico seja de intensidade leve ou moderada, de força ou de resistência aeróbica, pode sim ser uma fonte benéfica e terapêutica para indivíduos portadores de HIV/AIDS. Em conclusão, o exercício físico contribui e muito nas alterações físicas e fisiológicas para pessoas portadoras de HIV/AIDS. Sendo assim, uma boa periodização de treinamento deve ser realizada para manutenção da qualidade de vida dessas pessoas.
INTRODUCTION: High blood pressure is a systemic disease which has major clinical and psycho-social repercussions, involves a high morbidity-mortality rate and generates high costs for the health system. Its treatment involves the use of antihypertensive drugs, which are commercialized as trademark, generic or similar drugs. PURPOSE: To verify the antihypertensive effect produced by a similar dose of different trademarks of enalapril maleate in spontaneously hypertensive rats (SHR). METHODS: Fifteen mg/kg of enalapril maleate were administered by gavage in 50 SHR rats and their blood pressure was verified through tail plethysmography every three days in a period of 16 days. RESULTS: The group treated with reference drug has shown a significant reduction on blood pressure levels when compared to the control group. Thus, treatments with enalapril maleate of generic, similar-A and similar-B brands have also shown significant reduction on animals' blood pressure. CONCLUSION: The use of generic drug and similars (A and B) drugs in the same doses and for the same period of time has not shown significant difference regarding the reference drug, which suggests that the brands tested are bioequivalent.
54,6AE11,0 years. Risk factors for thrombosis were the indication for ACO in 9 (60%) including arteriovenous fistula or hemodialysis catheter thrombosis and previous graft loss due to thrombotic event. In the remaining 6 (40%) OAT indication was AF. Eight patients (53,3%) were in concomitant use of Antiplatelets. Median INR in admission test was 2,2AE1,0. On 12 patients (80%) the reversion therapy was vitamin K and fresh frozen plasma. The remaining 3 (20%) had INR < 1,5, dismissing treatment. Surgical excessive bleeding requiring transfusion were observed in 7 (46,7%) patients, and there were 02 deaths related to these complications. Re-introduction of OAT was necessary in 8 (53,3%) individuals. There was no statistical difference between long term renal graft function, with a median MDRD of 57,55 and creatinine of 1,6 after 5 years.CONCLUSIONS: Oral anticoagulants use adds surgical risks for bleeding complications and death in kidney transplant recipients, independently of anticoagulant reversal therapy.
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