E-Learning as a new platform of training has attracted a lot of attention from researchers and practitioners in recent years. Many researchers tried to assess different factors which influence E-Learning outcomes. This study aims to examine seven most important factors which exist in the literature (including content, support, ease of use, reliability, computer self-efficacy, expert and culture) using an empirical approach. Participants are 247 students who are using technology-based education in Iran. Regression results showed that five variable including supports, ease of use, reliability, computer self-efficacy and culture, have a significant influence on E-Learning outcomes but two other variables including content and expert don't show a significant effect. Also results of principle component analysis and latent moderated structuring (LMS) method reveal that "technical support" is the most important variable which affects web-based education.
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