Tribolium castaneum es una plaga que infesta los productos agrícolas almacenados, principalmente granos. Una alternativa de control son los productos naturales, destacándose los aceites esenciales. Se evaluó la actividad repelente del aceite esencial de Bursera graveolens Jacq. ex L. contra T. castaneum aplicando el método de área de preferencia. Los resultados muestran diferencias significativas (p menor que 0.005) entre el área tratada y no tratada en las dosis 0.02, y 0.2 µL/cm2 luego de dos horas de exposición. Dicha actividad decreció al aumentar el tiempo de exposición. En conclusión, el aceite esencial de B. graveolens podría ser un repelente efectivo contra este insecto plaga. Tribolium castaneum (Herbst, 1797) is a plague that infest store products, mainly grains. One alternative to control it is the use of natural products, highlighting the essential oils. It was evaluated the repellent activity of the essential oil of Bursera graveolens Jacq. ex L. towards T. castaneum. Results shows significant differences (p less than 0.005) between the treated area and the non trated area at 0.02, and 0.2 µL/cm2 doses after two hours of exposition. Repellent activity decreased when the time of exposition increased. In conclusión, the essential oil of B. graveolens could be an effective repellent against plague insects, being also this report the first related to repellency in this plant.
Since early May 2022, numerous cases of Monkeypox (Mpox) have been reported globally in non-endemic areas. However, despite numerous reports worldwide, the epidemiological and genomic information related to the 2022 multi-country outbreak remains scarce in South America. By late June 2022, the first Mpox cases were detected in Colombia. Cartagena is a Colombian Caribbean city with high domestic and international connectivity, and, therefore, is vulnerable to the introduction of the Monkeypox virus (MPXV). This report provides an in-depth description of the epidemiological, clinical, and virological characteristics of the first four cases detected in Cartagena including three cases with no history of recent travel and one imported case. Using various laboratory tools based on PCR, next-generation sequencing, and viral isolation and quantification methods, the MPXV clade IIB was detected and isolated. Importantly, infectious viral particles were identified in lesion swabs collected from all cases and in oropharyngeal swabs collected from two cases. Blood samples tested negative using PCR and isolation. In summary, our work contributes complete genomic, clinical, and epidemiological information that will be useful for a number of studies going forward, and it also documents local information that contributes to our understanding of Mpox at the local level.
Rectal cancer (RC) is one of the most common malignant neoplasms, and cancer stem cells (CSCs) of the intestinal tract have been implicated in its origin. The oncofetal protein OCT4 has been linked to neoplastic processes, but its role and clinical significance in RC are unknown. This study investigates the expression of the stem cell marker OCT4 related to clinical-pathological characteristics and its clinical significance in RC patients. The expression level of stem cell marker OCT4 was analyzed in 22 primary rectal tumors by western blot. The association between OCT4 protein expression and the clinical-pathological features of tumors was evaluated by χ2 test and Fisher’s exact test. We demonstrated that the expression of the stem cell marker OCT4 was observed in tumor tissue but not adjacent non-tumor tissue. High expression of the stem cell marker OCT4 was significantly associated with histological differentiation grade (p = 0.039), tumor invasion level (p = 0.004), lymph node involvement (p = 0.044), tumor-node-metastasis (TNM) stage (p = 0.002), and clinical stage (p = 0.021). These findings suggest that high OCT4 expression is associated with a more aggressive RC phenotype, with a greater likelihood of progression and metastasis. These results shed light on the importance of targeting this CSC marker to attenuate RC progression.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.