Photoreduction of pyridine N-oxide, which has a key structure of antitumor agents for hypoxic solid tumors, by 1-benzyl-1,4-dihydronicotinamide in deaerated aprotic media resulted in generation of hydroxyl radical, leading to the oxidation of salicylic acid to 2,3- and 2,5-dihydroxybenzoic acids, and catechol.
The carbon-13 nuclear magnetic resonance spectra of l-aryl-3,3-dialkyl-l-nitrosoureas and related compounds were measured at about -40•Ž, and their chemical shifts were assigned. The conformations of the N-nitroso compounds having the l-aryl-l-nitrosoureido group were established through comparisons with N-alkyl-N-nitrosoanilines, and the decomposition mechanism of l-aryl-3,3-dialkyl-l-nitrosoureas is discussed on the basis of the results.
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