A 57-year-old woman with primary intracerebral osteosarcoma is reported. The tumor was identified by computed tomography as a mass with hemorrhage in the right parietal lobe. The surgical and pathological examinations confirmed an osteosarcoma of intracerebral origin. She suffered from repeated local recurrence of the tumor and died about 1 year after the onset. The pathological findings showed features of osteoblastic osteosarcoma with numerous osteoclast-like multinucleated giant cells. Immunohistochemically, tumor cells were positive for vimentin, and partially for actin. Multinucleated giant cells were reactive with vimentin and CD68 antibodies. Ultrastructurally, tumor cells were rich with rough endoplasmic reticulum. These findings are consistent with the histological features of skeletal or extraskeletal osteosarcoma. This is the third case of primary intracerebral osteosarcoma reported in the literature and the first one analyzed ultrastructurally.
Left transverse sinus thrombosis developed in a 27-year-old male with ulcerative colitis. The diagnosis was based on cerebral angiography and magnetic resonance (MR) imaging, the latter of which clearly delineated the intraluminal thrombus. Serial MR images demonstrated thrombus organization. The use of this method in the diagnosis of cerebral sinus thrombosis might reduce the need for cerebral angiography.
To our knowledge, there are no published papers detailing antisepsis for injection sites. In view of this, the efficacies of povidone-iodine (PVP-I) ethanol solution and chlorhexidine (CH) ethanol, the agents most commonly used for antisepsis of the operative field, were compared. Before and after the injection site was disinfected with either of these antiseptics, specimens of indigenous bacteria on the skin were collected by the cylinder scrub method, and the bacteria reduction rate and the reduction factor (RF) were determined to evaluate the efficacy of antisepsis. The bacteria reduction rate and RF value obtained for PVP-I ethanol were 95.1 ± 11.2 and 2.1 ± 0.9% and those for CH ethanol were 93.5 ± 9.3 and 1.8 ± 0.9%. Since there were individual differences in cell count before antisepsis, no significant difference was seen in bactericidal activity. However, slightly more favorable results were obtained with PVP-I ethanol. Although it is impossible to eradicate completely the indigenous microbes with currently available methods, it is considered important for the prevention of infection of the injection site to decrease bacterial counts as much as possible.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.