Artificial neural network (ANN) is tested as a tool for finding a new subgrid model of the subgridscale (SGS) stress in large-eddy simulation. ANN is used to establish a functional relation between the grid-scale (GS) flow field and the SGS stress without any assumption of the form of function.Data required for training and test of ANN are provided by direct numerical simulation (DNS) of a turbulent channel flow. It is shown that ANN can establish a model similar to the gradient model.The correlation coefficients between the real SGS stress and the output of ANN are comparable to or larger than similarity models, but smaller than a two-parameter dynamic mixed model. *

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