We describe a 72-year-old man with mycosis fungoides (MF) followed up at our hospital for more than 20 years, who has developed 14 eccrine poromas (EPs) in the past 12 years. Twelve of these tumours were ascertained as EP histopathologically without any findings of malignancy and the other two were clinically diagnosed and are not yet resected. To our knowledge, this is the first case report of MF complicated with multiple EPs. In our patient, all EPs arose in skin areas previously irradiated with an electron beam for the treatment of MF, suggesting that electron beam irradiation might have an effect on the development of EPs.
Special types of syringoma include eruptive syringoma (1) and syringoma on the vulva and on the upper extremities (2). We present a large one, 1×5 cm in size, found on the right side of the neck, and preoperatively diagnosed as nevus sebaceus.
Two cases of congenital onychodysplasia of the index fingers (COIF), one of them with an abnormal range of active motion of the digits, were reported. The characteristic location of a nail, or nails in micronychia and polyonychia of COIF and the involvement of the nail and the bone may be explained by the anatomy of the digit. That is, the radially more pronounced involvement of the nail may be related to the relatively smaller size of the artery of the radial aspect. This may support the transient ischemia theory of Ohta and Haseda (1) in fetal life, though the true etiology of COIF still remains obscure.
CASE REPORTSCase 1. A 24-year-old female, otherwise healthy, has had since birth a small nail, 1.6mm in
Erythema dyschromicum perstans (EDP) is a peculiar pigmented condition of unknown etiology, resistant to any treatment (1-3). We report a typical case of EDP and discuss its differential diagnosis.
CASE REPORTA 50-year-old farmer was referred to Miyazaki Medical College in November of 1978 for slower progressing pigmentation of 4 to 5 years' duration chiefly involving the torso and proximal aspects of the extremities. There had occasionally been mild pruritus. He had no significant drug history. His family and past history were noncontributory .Examination revealed rounded or geographically shaped gray and brown macules scattered over the trunk and extremities (Fig. 1). Some of the gray lesions were encircled by a ring of elevated erythema (Fig. 2). There were slightly scaling erythematous macules and brown lesions of varying shapes and intensities (Fig. 3). There was mild lymphadenopathy in the axillae and inguinal regions. New lesions of gray pigmentation were well bordered against normal skin, while older ones tended to be ill-defined.Delayed type hypersensitivity to PPD and Candida antigen was negative, although DNCB sensitization was achieved. Other laboratory data were essentially negative. Histological examination of an erythematous border in the abdomen revealed an atrophic epidermis containing microvesicIes and small round cells (Fig. 4); atrophied but deeply projected rete ridges, edema and a mild lymphocytic infiltration into the papillary layer of the dermis. Melanin granules were increased, partly in the basal layer, and there was incontinence of pigment ( Fig.
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