Background: The number of patients with colostomy is increasing every day. Caring of patients with colostomy after operation should be based on different aspects of their quality of life (QoL). This study was conducted to determine the effect of telephone counselling (telenursing) by nurses on the QoL of patients with permanent colostomy. Methods: This research was a randomized clinical trial study with the control group. It was conducted on the patients referring to Iranian Ostomy Society, Tehran, Iran. At first, a total of 70 patients with permanent colostomy were selected by convenience sampling method and then randomly assigned in the experimental group (with telephone counselling) and control group. Patients in both groups followed training sessions as usual and participated in it. Data collection tool was City of Hope-quality of life-Ostomy questionnaire. QoL was measured at the beginning of the intervention and then 16 weeks later. Statistical data were analyzed using descriptive statistics, paired t test, independent t test, and analysis of covariance. Data analysis was performed by SPSS version 22. Results: After telephone counseling, significant differences were observed between two groups with regard to physical (P=0.007), mental (P˂0.001), and social (P˂0.001) aspects of patients' QoL. Regarding the spiritual aspect of QoL, no significant difference was found between two groups (P=0.111) after telephone counselling. All in all and compared with the control group, telephone counselling was significantly effective on the patients' QoL (P˂0.001). Conclusion: Based on the results, telephone counselling was effective on physical, mental, and social aspects of patients' QoL and can be used to improve the QoL and health of the patients with colostomy. In this regard, nurses as the main members of the health staff can use telephone counselling program to help their patients.
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