A new strategy to access conjugated allenynes via a decarboxylative coupling of propargyl esters of propiolates has been developed. In this process, allenyl-palladium intermediates are coupled with acetylides that are generated in situ to form the conjugated allenynes. Finally, the coupling is demonstrated to be highly stereospecific, providing a route to enantioenriched allenes.
Most early childhood teachers would tell you that creativity is important; and that creativity should be considered an integral part of every early childhood classroom. Yet, too often, it is slighted in some areas or limited to being a part of art education. How can creativity can be nurtured and developed in all cognitive and social aspects of an early childhood classroom? The key to this fostering of creativity is for each teacher to examine his or her own filters that can help to foster, or hinder, as the case may be, creativity in that classroom setting. By examining adult attitudes, classroom atmosphere, and children's activities and materials, and adjusting, where necessary, to incorporate certain positive elements for creativity, early childhood educators are more likely to establish a trusting, flexible, and safe environment that allows and stimulates the creative process in an atmosphere of respect.
The rhodium‐catalyzed addition of polyfluorobenzoic acids to butadiene led to a range of branched and linear allylic esters, with preference for the formation of the branched isomer. This method provided branched fluorinated esters in an atom‐economical catalytic addition reaction. The observation that the yield of the addition product depended on the acidity of the starting acid led to the hypothesis that the addition reaction was reversible and thus thermodynamically controlled. Deuterium‐labeling and crossover experiments supported this hypothesis. Ultimately, the dependence of yield on the pKa as reported in this paper may help to guide approaches to high‐yielding additions of acids to dienes.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.