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Implications and Contribution: Evidence from this literature review provides guidance from the Pediatric Initiative Network of the Oncofertility Consortium for health care providers establishing a pediatric fertility preservation program.

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FP is both safe and efficacious for eligible cancer patients. Only 10% of patients returned to use cryopreserved specimens, and almost half used a gestational carrier, suggesting the need for further research into reproductive decision-making in cancer survivors.

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