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Although colorectal cancer screening is highly effective in reducing mortality, only 60% of adults are up to date with the tests recommended by current guidelines. Consequently, researchers and clinicians are eager to find ways to improve screening rates. A recent study by John Z. Ayanian, MD, MPP, and colleagues assessed and compared the effectiveness of 2 strategies for increasing colorectal screening: (1) mailing reminders to patients who were overdue for colorectal cancer screening, and (2) issuing electronic medical record reminders to their physicians (Archives of Internal Medicine 2009;169:364-371).