Novel inorganic-organic hybrid photochromic and fluorescent ink for anticounterfeiting documents was developed using a pigment/resin ink formula enclosing a long-lived luminescent inorganic pigment with good thermal photostability. The produced ink exhibited an optimal excitation wavelength at 360 nm
Background: Vitiligo is a dermatological disorder characterized by functional melanocyte loss, affecting 1% of the global population. The prevalence and impact of thyroid hormone and autoantibody levels on pediatric patients with vitiligo remain unclear. Aim: This study aims to assess the incidence of autoimmune thyroid disorder in pediatric vitiligo patients and investigate the impact of thyroid hormone and autoantibody levels on vitiligo activity. Subjects and Methods: A total of 68 children with vitiligo participated in this cross-sectional study, which included measurements of thyroid function, autoantibody tests, and examinations of the patients' vitiligo type, duration, activity, and onset. Results: Autoimmune thyroiditis was detected in 33.8% of patients. Positive anti-thyroglobulin antibodies were significantly associated with a family history, duration, and activity of vitiligo. Positive anti-thyroid peroxidase antibodies were significantly related to active vitiligo, sudden onset, and higher TSH levels. Anti-thyroglobulin antibodies correlated positively with age, duration, and TSH levels but negatively with T3 and T4 levels. Anti-thyroid peroxidase antibodies were positively correlated with TSH. Positive anti-thyroglobulin antibodies extended disease duration. Active vitiligo and rapid onset were more frequent with positive anti-thyroid peroxidase antibodies. Conclusions: This study concluded that pediatric vitiligo patients, particularly females and those with a family history of autoimmune diseases, have a higher frequency of thyroid dysfunction and autoantibodies. Moreover, regular monitoring of thyroid function and autoantibodies among pediatric patients with vitiligo is important to detect progression to overt hypothyroidism. Consequently, practitioners should recognize and treat thyroid-related conditions early and be aware of the relationship between vitiligo and autoimmune thyroid disease.
Introduction: The periodontal ligament is a complicated connection tissue system connecting the alveolar bone to root surface, like any other tissue periodontal ligament undergoes changes by age either in its fibers, ground substance, cells or blood vessels. Aim of the work: This work aimed to assess the histological changes of periodontal ligament in different ages of albino rats and correlating these changes with corresponding human ages. Material and Methods: 30 rats were divided evenly into 2 groups (15 rats each). Group 1: 6 months old group and Group 2: 24 months old group rats. Rats were terminated by I.V. overdose of sodium thiopental, the mandibles of the rats were excised to allow for laboratory processing for H&E stain, Masson's trichrome stain and Periodic acid-Schiff (PAS) with subsequent examination, 30 periapical films from two categories of persons aged between 16-18 years and 68-72 years old. Results: Histologically, group 2 showed significant reduction in immature fibers, cells and ground substance. Statistically, regarding morphometric analysis of periodontal ligament width in periapical human films, there were no significant difference in width between oblique and apical regions in both rats and human. Both experimental rats and human showed increased PDL width by age Conclusion: There is gradual reduction in fibers and cellularity of periodontal ligament by aging. However, periodontal ligament width mostly increased by age in rats and in examined periapical films in human.
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