A solid phase extraction (SPE) system for sesquiterpene lactones of damsissa was developed utilizing molecularly imprinted polymers (MIPs). The prepared MIPs had a mesoporous structure and particle size of ≈2.65 µm with 3.99 nm pore size. Additionally, MIPs exhibited high thermal stability with degradation temperature between 209 and 459 ⁰C.Optimized MIP-SPE protocol conditions were set at loading step: 1 mL ethanol; washing step: 1 mL water; eluting step: 4 mL methanol. Developed MIP-SPE system showed a binding capacity of 66.66 mg/g based on Langmuir isotherm which was selected as the best fitting model isotherm. Good selectivity coefficients were observed for neoambrosin of 2.37, 1.31 and 1.14 against umbelliferone, quercetin glucoside and p-coumaric acid, respectively.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.