In the version of this article initially published online, there were two errors. In the section "Three classes of monoallelic elements" in the main text, "We classified all monoallelically accessible elements (1,966 elements)" should have read "1,964 elements. " In the legend for Figure 5c, the number of elements open in ESCs should have been given as 234 instead of 35.

BackgroundTo help families protect children from injury, we have to reach them in channels they are tuning into using messages that resonate. Today’s parents are getting much of their information through channels that didn’t exist ten years ago. Safe Kids has undergone a messaging transformation, changing our tone, simplifying our messaging for low-literacy audiences and building new media channels to connect with parents.We conducted a series of focus groups among mothers and grandmothers.We recruited from two populations: low literacy and average literacy. The topic was medication safety.We also tested several types of posts on Facebook, tracking engagement.ObjectiveThe objective of this session is to educate injury professionals on strategies for connecting with today’s families.The culture of communications has changed dramatically in the last ten years. As safety experts, we need to evolve how we reach today’s families.ResultsWe learned the best way to present messages to parents so they are intrigued to learn more. We also learned when it helps to include statistics and when parents tune statistics out.To address channels, we tested several social media strategies to determine which ones deliver the best results. Our success is evident in our growth. In just four years, our Facebook page has grown from 35,000 likes to more than 1,000,000 likes.ConclusionsTo impact the culture of safety, we need to understand the culture of communicating to today’s parents so we can meet parents where they are. Safe Kids Worldwide is eager to share what we have learned about tone, messaging and communications channels. In conversations at past conferences with injury professionals around the world, we believe this is a topic of universal interest and essential for connecting with families to reduce injuries in children in the future.

Landraces (traditional varieties) of crop species are a reservoir of useful genetic diversity, yet remain untapped due to the genetic linkage between the few useful alleles with hundreds of undesirable alleles1. We integrated two approaches to characterize the genetic diversity of over 3000 maize landraces from across the Americas. First, we mapped the genomic regions controlling latitudinal and altitudinal adaptation, identifying 1498 genes. Second, we developed and used F-One Association Mapping (FOAM) to directly map genes controlling flowering time across 22 environments, identifying 1,005 genes. In total 65% of the SNPs associated with altitude were also associated with flowering time. In particular, we observed many of the significant SNPs were contained in large structural variants (inversions, centromeres, and pericentromeric regions): 29.4% for flowering time, 58.4% for altitude and 13.1% for latitude. The combined mapping results indicate that while floral regulatory network genes contribute substantially to field variation, over 90% of contributing genes likely have indirect effects. Our strategy can be used to harness the diversity of maize and other plant and animal species.