F. nucleatum
colonizes various human tissues, including oral cavity, placenta, and colon. How this obligate anaerobe withstands oxidative stress in host immune cells has not been described.
Fusobacterium nucleatum
is a key commensal anaerobe of the human oral cavity that plays a significant role in oral biofilm development and contributes to additional pathologies at extraoral sites, such as promoting preterm birth and colorectal cancer. Although
F. nucleatum
is known as a major producer of hydrogen sulfide (H
2
S), its genetic determinants and physiological functions are not well understood.
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