Hemodynamic changes are involved in the cyclic remodeling of ovarian structures. A transrectal color Doppler ultrasonography was used to assess the blood flow and changes in the vasculature that take place in the follicle wall and within the corpus luteum (CL) during specific physiological events such as ovulation, CL development, and CL regression in cows. To investigate the local release of vasoactive peptides, steroid hormones, and prostaglandins (PGs) in the ovarian microenvironment, the capillary membranes (0.2 mm diameter and 5-10 mm length) of a microdialysis system (MDS) were implanted into the follicle wall and the CL in vitro. Furthermore, in vivo experiments were conducted with the same MDS membranes surgically implanted in follicle wall or on CL along with ovarian venous and jugular catheters to collect simultaneous, real-time information on the ovarian and systemic changes in the secretion of factors regulating vascular function. Based on the results obtained from the series of in vitro and in vivo experiments, we propose that a functional "cross-talk" occurs between the vascular components (endothelial cells) and steroidogenic cells to control follicular and luteal functions in the bovine ovary.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.