Clinical manifestations of drug-induced skin reactions include a wide range of symptoms, from mild drug-induced exanthemas to dangerous and life-threatening generalized systematic reactions. Adverse drug reactions of low risk include phenomena such as drug-induced rashes, phototoxic reactions, eczemas and urticarias, which appear most often when the medication is being introduced. Drug-induced skin reactions to psychotropic medication are usually associated with antiepileptic drugs. However, a significant role can be assigned to selective serotonin reuptake inhibitors. The aim of this paper is to review a spectrum of severe skin complications in patients treated with antidepressants with the indication of their clinical monitoring and management.
DRESS diagnosis should be taken into consideration especially in patients treated eith antiepileptic drugs. Early diagnosis and drug discontinuation can contribute to preventing serious complications of DRESS.
Obesity affects over 600,000 people in Poland, and bariatric surgery is a vital part of the multidisciplinary approach to treatment. To improve outcomes, Poland’s public health institutions implemented the KOS-BAR programme, a multicentre nationwide pilot initiative that includes psychiatric evaluations of patients. The aim of this study was to assess the prevalence of mental disorders, verify diagnoses, and evaluate pharmacotherapy efficacy for patients under psychiatric treatment and selected for bariatric surgery. Of the 180 patients evaluated, 40% had a history of mental disorders, with depressive and eating disorders being the most common diagnoses. Patients selected for revision surgery had a higher incidence of depressive and compulsive eating disorders. Psychiatric support can improve patient cooperation and optimize long-term outcomes after bariatric surgery. A more complete evaluation of the psychological profile and depressive disorder’s impact on bariatric treatment outcomes will be the next step for this group of patients.
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