Inspired by studies demonstrating the potential for new myocyte formation within adult mammalian hearts, an ongoing explosion of research is elucidating the biology of cardiac myogenesis and angiogenesis. Multiple lines of research suggest that disease-associated activation of endogenous cardiac repair processes are often insufficient to overcome the cell death resulting from myocardial infarction and chronic heart failure. In this context, this review highlights current evidence supporting endogenous cardiac repair mechanisms in human hearts, recent progress with clinical application of myocardial cell therapy, and complementary efforts to manipulate endogenous myocardial repair processes using a variety of tissue engineering strategies. The goal of this overview is to demonstrate that the insights and opportunities derived from each of these lines of inquiry are mutually complementary for ultimately achieving the goal of therapeutic cardiac regeneration.
La explotación sexual comercial infantil y adolescente (ESCIA) es un problema especialmente frecuente en niños, niñas y adolescentes con medidas jurídicas de protección. Esta forma de victimización sexual, que recoge otras múltiples formas de violencia, no sólo está presente en países en vías de desarrollo. En España, únicamente contamos con los datos obtenidos por la Comisión de Expertos de Mallorca en 2020. Se presentan las respuestas de 67 adolescentes, entre 13 y 18 años, en centros residenciales del sistema de protección, sobre sus conocimientos y experiencias respecto a la ESCIA. Los resultados indican que se trata de un problema conocido y ante el cual demandan más educación y protección. Aluden a motivos diversos para implicarse en él, pero todos ellos pueden situarse dentro de la pirámide del sexo por supervivencia. El uso de las TIC aparece como un importante factor de riesgo a tener en cuenta en programas de prevención.
This paper presents TransDic, a free distribution tool for the phonetic transcription of word lists in Spanish and Catalan which allows the generation of phonetic transcription variants, a feature that can be useful for some technological applications, such as speech recognition. It allows the transcription in both standard Spanish and Catalan, but also in several dialects of these two languages spoken in Spain. Its general structure, input, output and main functionalities are presented, and the procedure followed to define and implement the transcription rules in the tool is described. Finally, the results of an evaluation carried for both languages are presented, which show that TransDic performs correctly the transcription tasks that it was developed for.
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