Objective: The present research seeks to examine the diagnostic accuracy of magnetic resonance spectroscopy in the diagnosis of malignant breast lesions using histopathology as the gold standard. Study Design: Cross-sectional Place and Duration: Sadiq Abassi Hospital Bahawalpur. July-21 to Dec-21 Methods: There were 110 females were presented in this study. Patients had with suspicious palpable lesions for malignancy were included. Before any patient data was collected, they signed a permission form acknowledging they understood the risks. The kinetics and morphology of magnetic resonance spectroscopy (MRS) dynamically enhanced pictures acquired with contrast on 1.5 Tesla MRI equipment were evaluated. The choline peak (Cho) permitted by MRS was used to determine a malignancy biomarker.. Single-voxel approach was used to examine MRS' diagnostic performance in breast lesions malignancy. Comparing MRS and biopsy results was done. This version of SPSS 22.0 was used to analyse all the data. Results: Majority of the patients 50 (45.5%) were from age group 41-60years, 35 (31.8%) patients had age > 60 years and 25 (22.7%) were from age group 20-40 years. Frequency of malignant lesion by MRS was found among 92 (83.6%) cases and by histopathological results its frequency was 81 (73.6%). Ductal enhancement and peripheral enhancement were the most common morphology among patients of malignant lesion by MRS. According to MRS findings, 75% specificity,86.7% accuracy, 91%sensitivty, 79% negative predictive value (NPV) and 92.3% positive predictive value were found. Conclusion: As a main imaging tool for the diagnosis of breast lesion malignancy, MRS must be used because of its superior specificity, sensitivity, and accuracy in the characterisation of breast lumps. It has been discovered that MRS is a very specific, sensitive, and reliable diagnostic tool for detecting malignant breast cancers. Keywords: Malignant breast lesion, Histopathology, Magnetic resonance spectroscopy (MRS)
Objective: Purpose of our study is to diagnose accuracy of transvaginal versus transabdominal ultrasonography for diagnosing adnexal masses. Study Design: Cross-sectional/Comparative study Place and Duration: Sadiq Abassi Hospital Bahawalpur. March 2021 - Oct 21 Methods: There were one hundred and twenty females were presented in this study. Females were aged between 18-55 years. As part of the informed written consent process, all of the patients were asked to provide demographic information including their age, gender, monthly abnormalities (Oligomenorrhea / Amenorrhea), infertility, recurrent pregnancy loss, hirsuitism, and acne vulgaris and obesity. The location, size, borders, echogenicity, soft tissue component, septations, and nodularity of ovarian lesions were evaluated on a grey scale. Patients were equally divided into two groups, group I had 60 cases and received transvaginal ultrasonography while group II received transabdominal ultrasonography with MRI. Outcomes among both groups were compared in terms of frequency of adnexal mass by using histopathological findings (positive/negative). SPSS 25.0 version was used to analyze complete data. Results: There was no any significantly difference between age and body mass index among both groups. Mean parity in group I was 2.34±4.14 and I group II was 1.14±7.38. Infertility and irregular cycle was the most common complaints among both groups in 28 (46.7%), 26 (43.3%) and 21 (35%), 24 (40%). Frequency of adnexal mass in transvaginal ultrasonography was found among 32 (53.3%) but in group II (transabdominal ultrasonography) adnexal mass found in 36 (60%) cases. According to histopathological among 32 cases of transvaginal sonography 26 had true positive and 6 had false negative and in group II 32 cases had true and 4 cases had false positive results. We found that accuracy of transvaginal sonography was lower than that of transabdominal sonography in terms of specificity, positive predictive value and negative predictive value. Conclusion: We concluded in this study that abdominal ultrasonography with MRI was more beneficial and effective in terms of diagnosing adnexal masses with authentic values of specificity and sensitivity. Keywords: Adnexal Masses, Transabdominal ultrasonography, Transvaginal ultrasonography, Complications, Accuracy
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.