An efficient method to prepare N-acylpyridinium ions like (III) is reported. Treatment of the latter with organometallic reagents leads to α-substituted N-acyldihydropyridines and N-acyldihydropyridones. The degree of stereoselectivity depends on the pyridine and organometallic reagent used. The auxiliary can smoothly be removed under basic conditions. -(HOESL, C. E.; MAURUS, M.; PABEL, J.; POLBORN, K.; WANNER*, K. T.; Tetrahedron 58 (2002) 33, 6757-6770; Inst. Pharm.,
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