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This paper documents performance of cast-in-place reinforced concrete (RC) buildings in the Durrës during Albania earthquake of 26 th of November 2019 (M W 6.4). Both mid-and high-rise RC buildings were affected by the earthquake, experiencing structural and/or non-structural damage and even collapse in some cases. The authors performed a reconnaissance study after the earthquake and were involved in seismic assessment of buildings in the affected area. Besides the observations related to physical damage related to RC buildings, the paper also presents results of a statistical analysis of damaged RC buildings in the Durrës city. The discussion in the paper is focused on damage patterns and failure mechanisms that are relevant for the seismic response of RC structures. Most common damage pattern is related to masonry in ll walls, which experienced damage and failure in some cases, and affected the performance of adjacent RC columns due to the in ll/frame interaction. Taller RC framed buildings (10 storeys and higher) were expected to have RC shear walls; however, these walls were reportedly absent in the damaged buildings of this type. In some cases, masonry in ll walls (instead of RC shear walls) were used in the elevator shaft areas, which resulted in inadequate seismic performance. Two case study buildings were presented in detail to illustrate seismic behaviour of cast-in-place RC buildings. The case study is based on eld observations after the earthquake and a detailed seismic assessment study. Finally, relevant lessons and recommendations are presented in light of the observed performance of RC buildings.