For recurrent glioblastomas, an improvement in overall survival can be attained beyond an 80% EOR. This survival benefit must be balanced against the risk of neurological morbidity, which does increase with more aggressive cytoreduction, but only in the early postoperative period. Interestingly, this putative EOR threshold closely approximates that reported for newly diagnosed glioblastomas, suggesting that for a subset of patients, the survival benefit of microsurgical resection does not diminish despite biological progression.
The new scale accounted for increasing SAH thickness and was superior to the Fisher scale in inter- and intraobserver agreement and in predicting symptomatic vasospasm, particularly among the highest-risk patients.
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