Background: Uniportal video-assisted thoracoscopic surgery (VATS) is a challenging surgical procedure that poses substantial technical difficulties compared to multiportal VATS but has been associated with favorable outcomes in studies reported to date. Methods: On-line databases were screened until June 2016. Meta-analysis aimed to compare clinical outcomes of uniportal and multiportal VATS lobectomy for patients with lung cancer. Endpoints assessed included perioperative mortality, operative time and blood loss; length of hospital stay; duration of postoperative drainage; rates of conversion to open thoracotomy; number of harvested lymph nodes and overall morbidity. Risk Ratios (RR)/ Mean Difference (MD) and corresponding 95% Confidence Intervals (95%CIs) served as primary statistics.
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