Introduction: Among factors that underlie high rates of non-participation reported in telehealth interventions are the low older users' acceptance of information technologies and the low levels of non-compliance with therapy of chronic patients. Therefore, inclusion of potential users into design stages of assistive technologies is challenging. In this paper, the design, implementation and evaluation of a multimodal mobile application for telemonitoring chronic obstructive pulmonary disease (COPD) is presented. The goal of the study was to assess the usability and feasibility of the designed tool. Methods: An iterative user-centered design methodology was applied to implement a prototype that satisfied users' requirements. Feasibility (compliance, COPD knowledge and satisfaction) of the application was assessed in a 6-month field trial with COPD patients. Results: A usable, effective and efficient prototype was released after the development process. A high compliance (86.1%) and an increasing in COPD knowledge were achieved in the field trial. Conclusions: The findings reveal the importance of integrating usability in the design development processes to improve adherence to routine tasks and to reduce the high rates of non-participation reported in recent evaluation studies of telehealth interventions. The presented tool can help to recognize early symptoms of deterioration and to support patients in COPD self-management.
BackgroundDrug-drug interactions are frequently reported in the increasing amount of biomedical literature. Information Extraction (IE) techniques have been devised as a useful instrument to manage this knowledge. Nevertheless, IE at the sentence level has a limited effect because of the frequent references to previous entities in the discourse, a phenomenon known as 'anaphora'. DrugNerAR, a drug anaphora resolution system is presented to address the problem of co-referring expressions in pharmacological literature. This development is part of a larger and innovative study about automatic drug-drug interaction extraction.MethodsThe system uses a set of linguistic rules drawn by Centering Theory over the analysis provided by a biomedical syntactic parser. Semantic information provided by the Unified Medical Language System (UMLS) is also integrated in order to improve the recognition and the resolution of nominal drug anaphors. Besides, a corpus has been developed in order to analyze the phenomena and evaluate the current approach. Each possible case of anaphoric expression was looked into to determine the most effective way of resolution.ResultsAn F-score of 0.76 in anaphora resolution was achieved, outperforming significantly the baseline by almost 73%. This ad-hoc reference line was developed to check the results as there is no previous work on anaphora resolution in pharmalogical documents. The obtained results resemble those found in related-semantic domains.ConclusionsThe present approach shows very promising results in the challenge of accounting for anaphoric expressions in pharmacological texts. DrugNerAr obtains similar results to other approaches dealing with anaphora resolution in the biomedical domain, but, unlike these approaches, it focuses on documents reflecting drug interactions. The Centering Theory has proved being effective at the selection of antecedents in anaphora resolution. A key component in the success of this framework is the analysis provided by the MMTx program and the DrugNer system that allows to deal with the complexity of the pharmacological language. It is expected that the positive results of the resolver increases performance of our future drug-drug interaction extraction system.
The aim of this work is to establish some basic methodological aspects that should not be ignored in the arduous task of the development of telemedical platforms for the efficient control and management of chronic elderly patients. Among the main methodological proposed concepts should be: an integrated market-oriented approach, a usercentered design, an evaluation-driven development and a work plan organization. This work presents the methodology applied to Autonomy, Motivation,& Individual Self Management for COPD (Chronic Obstructive Pulmonary Disease) Patients (AMICA), project funded by the European Union (EU).
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