Introduction. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy is the most common monogenic disease of small blood vessels. It commonly presents with repeated episodes of brain ischemia leading to progressive subcortical vascular dementia, migraine attacks and mood disorders. Case Report. A 46-yearold male patient was admitted with clinical presentation of stroke. The neurological examination revealed mild divergent strabismus and a left homonymous hemianopia. Brain magnetic resonance imaging showed subacute infarction in the region of the posterior cerebral artery to the right, as well as similar lesions in the splenium of the corpus callosum, numerous mostly confluent and some discrete T2-weighted/fluid attenuated inversion recovery hyperintense lesions of the centrum semiovale, corona radiata, frontoparietal subcortex, capsula externa, periventricularly at the level of occipital and temporal horns of lateral chambers bilaterally, and small punctiform lesions in the region of the corpus callosum. The magnetic resonance angiography findings were normal. The patient's brother underwent neurological examination at the age of 42 due to severe headaches, double vision, confusion, and numbness in the right arm. The magnetic resonance imaging of the endocranium showed multifocal confluent ischemic lesions predominantly in the frontal and temporal lobes, as well as focal microangiopathic changes in the gangliocapsular regions bilaterally in the brainstem and cerebellum. In agreement with the patient and his brother, genetic analyses were performed in both of them, and a mutation in exon 3 of the neurogenic locus notch homolog protein 3 gene was confirmed (c.505C > t, p.R169C). Conclusion. Although there is no causal therapy, it is very important to diagnose cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy in order to implement measures to prevent cerebrovascular diseases in both patients and their family members.
An emergency caused by the COVID-19 pandemic affected the rethinking of existing healthcare systems. The increased need for hospital beds appeared short after the outbreak of the pandemic and the solution was to adapt the existing buildings, primarily public ones. Among all, sports buildings, i.e. sports halls were successfully used around the globe for conversion into hospitals. Topic of the paper was to investigate whether sports halls in Serbia, which were also used as temporary hospitals, are suitable for conversion in terms of energy consumption needed for achieving thermal comfort. Two case studies were analysed. The energy simulations were done using the DesignBuilder software. The results of thermal comfort summary and energy consumption led to the conclusion that this building type in Serbia could be successfully used for hospital purposes. Although the multiple increase in energy consumption was noted during the heating period, the results were within the limits required by both national and international standards.
Extensive urban development brings many adverse impacts which are reflected in degradation of quality of life and health of residents. Some of these impacts are related to increasing impermeable surfaces in city centers, made of concrete, asphalt, glass, etc. From environmental point of view, negative effects of urbanization include increased temperature and the effect of urban heat island which affects global warming, air pollution, flood risks and reduction of space for plants and animals. One of the ways to mitigate these effects is greening building envelope. This paper deals with ecological benefits which can be achieved by covering the building surfaces with greenery. Comparative analyses of buildings covered with greenery and with conventional materials were done based on data from certain studies conducted abroad. The results shown in the paper indicate a significant improvement in the living conditions in green covered buildings, and confirm that integration of vegetation represents a sustainable approach for the envelope of new and existing buildings. Key words: green roofs, green facades, urban environment, ecological benefits, sustainable design.
The use of renewable energies is imperative nowadays. One of the ways to use clean technologies is installation of photovoltaic systems which convert solar energy into electricity, through solar plants. The country?s potential for usage of solar energy is determined by the analysis of climatic conditions. The research is conducted on the example of a small-scale solar plant - a pilot project installed in the city of Nis, concerning the analysis of the mounted system and giving the recommendations for their design with the aim of improving efficient energy use. Limitations in the installation of solar plants can occur in the case of an unfavorable position of the building where the installation is planned, and more often, the limitations are related to the investment costs and length of the repayment period of these kinds of technologies. This paper represents a promotion of sustainable electricity supply for our country and it is in correlation with the legal directives of using renewable energies.
In times of radical social transformations, the demand for flexibility of space can be identified as one of the strategic priorities of maintaining the urban environment. In the context of social, economic and environmental sustainability, housing must imply an integrated ability to respond to programme changes, which can be achieved through the concept of flexibility. By identifying and applying certain design principles, it is possible to prevent the problem of functional obsolescence and unsuitability of the living environment that modern cities are facing. The apartment as an immediate living environment is the most direct indicator of the degree of adaptability of the physical surrounding to modern human needs. The analysis of basic design principles, using an example of flexible apartment, examines the spatial correlations and laws of the relationship between elements of the plan, which provides the basis for the authors to draw the conclusions about the reality of applying this concept in practice.
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